In this review:
Undiagnosed pancreatic exocrine insufficiency (PEI) results in malabsorption, which can quickly lead to gastrointestinal symptoms, weight loss, malnutrition, osteoporosis and fat-soluble vitamin deficiencies. Pancreatic replacement therapy (PERT) eliminates this malabsorption and sequelae by approximating the exocrine secretory response of a normal healthy pancreas. Dosing and administration of PERT is inextricably linked to diet, meaning that dietitians are ideally placed to prescribe and monitor this therapy. This review is supported by an educational grant from Viatris.
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